Genome, Phenome, Environment, and Evolution of Land Plants
Zhou, Xiaofan , Lin, Zhenguo , Quan, Li , McGovern, Jonathan , Ma, Hong .
Phylogenetic patterns of gene families and relationship with duplication mechanisms and function.
Gene family phylogenies can provide insights into the evolutionary history of genes, possible duplication mechanisms, and clues about possible gene functions. We have studied genes that regulate plant reproductive development and have used molecular evolutionary analysis to probe relationships among members of plant gene families. Our analyses revealed that plant gene families exhibit a wide range of different phylogenetic patterns, with vastly different rates of gene duplication. Several gene families, such as recA/RAD51, MutS/MSH, MutL/MLH, and SMC, show highly stable gene copy number over the entire history of land plant evolution, despite well-support genome duplications in both monocots (rice) and eudicots (Arabidopsis and poplar). Other families, such as the kinesin and histone demethylase gene families, have experienced moderate rates of gene duplications. In contrast, the SKP1 and Kelch-domain F-box gene families show very dramatic copy number expansions in specific lineages of plants. During angiosperm evolution, sometimes the same gene family can have some portions showing relatively stable copy numbers, whereas other portions with highly dynamic patterns. We present evidence for distinct mechanisms underlying the different patterns of gene duplications and discuss possible functional implications of such patterns. We also found that two relatively recent duplicates have diverged functionally.
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1 - The Pensylvania State University, Biology, 415 Life Sciences Building, The Huck Institutes of the Life Sciences, University Park, PA, 16802, USA
2 - Pennsylvania State University, Department of Biology, Institute of Molecular Evolutionary Genetics, and The Huck Institutes of the Life Sciences, University Park, Pennsylvania, 16802, USA
gene family evolution
low-copy nuclear gene
Presentation Type: Symposium or Colloquium Presentation
Location: Ballroom 2/Cliff Lodge - Level B
Date: Monday, July 27th, 2009
Time: 2:00 PM